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In a retrospective study of children with mitochondrial autism, 96% had markers of mitochondrial dysfunction in their blood: increased lactate level in 76% of the study group, an increase in pyruvate in 53%, an increased level of alanine in 36%, and CK activity was increased in 32% and 42% of the subjects who had abnormal organic acids in their urine [43]

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Mikamo, E., Harada, S., Nishikawa, J.-I

10.1042/bj0630514 Biochem