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Disclosures: mengyun ke: Nothing to Disclose, Jongwon Kim: Nothing to Disclose, Kate S Carroll: Nothing to Disclose, Wen Xie: Nothing to Disclose 2647 ANALYSIS OF NON-INVASIVE LIVER BIOMARKERS IN A PHASE II TRIAL OF THE GLUCAGON AND GLP-1 RECEPTOR DUAL AGONIST SURVODUTIDE IN PEOPLE WITH METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS (MASH) AND FIBROSIS Mazen Noureddin 1 Corinna Schoelch 2 Elisabetta Bugianesi 3 Naim Alkhouri 4 Mandy Fraessdorf 5 Jrn Schattenberg 6 Philip Newsome 7 Quentin Anstee 8 Guy Neff 9 Harvey Coxson 2 Eric Lawitz 10 Vlad Ratziu 11 Atsushi Nakajima 12 Azadeh Hosseini-Tabatabaei 13 Arun Sanyal 14 Ramy Younes 5 , 1 Houston Methodist Hospital, 2 Boehringer Ingelheim Pharma GmbH & Co

The central inset depicts Intravail (DDM) absorption-enhancing technology, which transiently increases nasal mucosal permeability to facilitate rapid systemic absorption of epinephrine, including during nasal congestion

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Int Rev Cell Mol Biol (2020) 354:10764

For example, in a controlled human 4 h PM 2.5 exposure (to a mean value of 37.8 g/m 3 ), a significant increase occurred in vascular inflammation and acute phase injury markers like serum amyloid A, C-reactive protein, soluble intercellular adhesion molecule-1, and soluble vascular cell adhesion molecule-1