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scRNA-seq on early passage TS543 neurospheres treated with RSL3 for one or three days demonstrated that the only glioma cell state signature significantly depleted at both time points was the astrocyte-like signature (Fig

Interestingly, the negative regulatory effect of APR-017 and LCS3 on GSH synthesis in VRK2-KO cells was reversed by VRK2 rescuing (Fig

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