Diabetes, 52(10), 2546-2553
Treatment with GLP-1RA significantly attenuated high glucose-induced tubule damage in DKD kidney tissues and TECs cells (177)
Increased serum salicylate concentration is associated with increased stimulation of respiratory centre in the brain and thereby hyperventilation, which results in increased carbon dioxide elimination and respiratory alkalosis (Chapter 7)
Many people with vitiligo seek ways to control and improve their symptoms
Complementary strategies include convection-enhanced delivery (CED) systems that enhance parenchymal drug distribution and chemical modifications (e.g., lipid group conjugation) to improve drug lipophilicity for BBB transit [109, 110]

Tailored routes of administration, ranging from enteral ozonated oil [ingestion], enteral ozonated water [ingestion], parenteral oxygen/ozone gas mixture [intramuscular, subcutaneous, intratonsillar, intrathecal, intraperitoneal, periganglionic, intraforaminal, paravertebral, intra-articular, intradiscal, oral submucous, supralaminar, epidural, penile, and intravenous], parenteral ozonated water [intra-tumoral], systemic [minor autohemotherapy (MiAH), major autohemotherapy (MAH), extracorporeal blood oxygenation and ozonation (EBOO), intravenous, and rectal insufflation], topical ozonated water [wound wash, ozonized balneotherapy, mouth wash, irrigation (nasal, sinus, otological, vaginal, intrauterine, intestinal, and intravesical), and sauna therapy, topical oxygen/ozone gas mixture [insufflation (ontological, intrafistula, intrauterine, and intravesical) and hyperbaric bagging], topical ozonated oil [embrocation and inhalation], and topical ozonated saline solution [wound wash, mouth wash, irrigation (saline, ontological, vaginal, intrauterine, and intravesical)], highlight its versatility [18, 25,26,27]
