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To evaluate the capacity of USPB@SeDMSN@NM for improving the polarization of pro-inflammatory M1 macrophages toward the anti-inflammatory M2 macrophages, RAW264.7 Cells treated with or without LPS (1 g/mL) for 24 hours, following different treatments for 24 h were harvested and lysed on ice using RIPA lysate (Beyotime, China) containing protease inhibitor cocktail on ice for 40 min

By replenishing the body's master antioxidant, this therapy neutralizes oxidative stress, restores cellular function, and promotes healthier metabolic activity

Rosenberg, N

10.1016/j.ophtha.2017.08.008 62 LandowskiM.BowesR

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For example, impaired mitochondrial metabolism in NAFLD impairs FA oxidation processes (e.g., mitochondrial beta-oxidation) and induces elevated DNL, which ultimately continues to drive NAFLD progression in the form of lipid accumulation [39, 40]