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BMC Genomics 16:S4

This has been proven in mice: Valproic acid induced histone hyperacetylation had brain function effects on the next generation of mice through changes in sperm DNA methylation

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A decrease in SCFA-producing bacteria, especially butyrate producers like Faecalibacterium and Roseburia from the Firmicutes phylum , along with certain Bacteroides species, has been observed in ME/CFS patients [10, 25, 28]