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In another study using gestating sows (mature female pigs that have farrowed at least once before the current gestation), Musser et al

Besides, activation of IKK, a component of IKK complex, can also directly phosphorylate IRS-1 serine to interfere its activation

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It is important to distinguish between excessive supplementation and pathologically elevated B12 levels, which may indicate underlying haematological disorders, liver disease, or renal impairment rather than true overdose

Xenograft tumor model Inclusion and exclusion criteria: no animals or experimental units were excluded from the study unless they met pre-defined humane endpoint criteria (e.g., ulceration, impaired mobility, or tumor burden exceeding institutional limits)