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92 RadhakrishnanR.HashemA.Abd_AllahE

Studies have shown that using small molecule EP4 antagonists, such as ONO-AE3-208 and AH23848, or silencing the EP4 gene, can significantly reduce the metastatic potential of RCC in preclinical models

(PubMed) Brown SB, Reeves KW, Bertone-Johnson ER

In cpr5 mutant trichomes, the endonuclear replication cycle stops after two rounds instead of four, and the trichome cells are less branched than normal