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The spatial-temporal expression analysis of the key genes in each module through BEST (Brain Expression Spatial-Temporal) indicated COVID-19 may induce impairment of sensory systems, memory, and cognition

If an excessive dose is required to achieve the relevant pharmacological activity, can it be reasonably assumed that it has no activity at lower doses and, thus, that they are not pharmacologically relevant

N., Masino S

Acting centrally rather than primarily on blood vessels, its commonly taken on demand, effects may begin within hours and can last up 2436 hours in some individuals