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A cell-autonomous signature of dysregulated protein phosphorylation underlies muscle insulin resistance in type 2 diabetes

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It is reported that with aging, the level of succinate decreases, which can be restored by phytochemical supplementation[65,66]

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Moreover, under oxidative stress, although autophagy initiation signals are activated in granulosa cells, impaired lysosomal acidification and mitophagy defects disrupt autophagic flux (Xu G

The findings showed that rabbits treated with AOD9604 demonstrated improved joint outcomes compared to control animals, with less morphological and histopathological cartilage damage