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[17] Physiologic B12 requirements increase during gestation, and parenteral cyanocobalamin is considered appropriate when dietary intake or intestinal absorption is inadequate

Its disease progression is relatively insidious, eventually evolving into heart failure with preserved ejection fraction

doi: 10.1186/s12964-022-00876-6 95 RezqSHuffmanAMBasnetJAlsemehAEdo CarmoJMYanes CardozoLLet al

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Instead, the new carbonoxygen bonds are created by using an acyl hydroperoxide both as substrate and oxygen donor, in essence acting as a dehydratase