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Besides, novel delivery systems have been reported to successfully increase the stability and solubility of SFN in recent years, such as coated microparticles, microencapsulation, and nanoparticles, and these strategies for improving the stabilization of SFN have been discussed in a recent review (Yuanfeng et al., 2021)

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10.1021/cr60156a002 [DOI] [Google Scholar] Shi Y

By enhancing the delivery of essential nutrients to avascular tissues, liposomal vitamin C provides a biological fast-track for tissue regeneration that was previously thought impossible with standard supplementation

Cultures were induced overnight at 28C and pelleted the following day before being frozen at -80C for future use