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In the field of delivery technology, targeting the unique joint anatomy and pathological environment of OA, developing biodegradable sustained-release carriers such as smart responsive nanogels, porous microspheres, or tissue engineering scaffolds is key to achieving long-term and controlled release of GPX4 genes, regulatory miRNAs or ASOs, or small molecule ferroptosis inhibitors at the lesion site (Wang Y

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Bronstein, "Neurotoxicity of the Parkinson's Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos", Environ Health Perspect 124 (11): 1766-1775 (2016)

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Fasting glucose levels were also similar between these 2 groups (Supplemental Figure 5G)

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It is a neuroendocrine reset one that creates the biological conditions for recovery sleep rather than forcing it

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CA: Cancer J Clin

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