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DSIP differs in that it directly modulates neuropeptide and neurotransmitter pathways associated with sleep induction rather than acting primarily as a circadian signal

Although current data support the notion that HDACi overcomes resistance through epigenetic regulation and inhibition of pro-survival pathways, the limitations of small sample sizes and non-randomized designs necessitate validation through larger-scale studies (102)

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Similar content being viewed by others Introduction In its role as the principal detoxification organ, the liver is highly exposed to environmental toxicants, pharmacological compounds, and dietary ingredients

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