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[48] Severe hepatic impairment may represent a relative contraindication to ondansetron use, as the drug undergoes extensive hepatic metabolism

Furthermore, mitochondrial dysfunction is a feature common to the monogenic and sporadic forms of PD

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Research published in GeroScience found that SS-31 specifically improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)