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The KEYNOTE-522 trial ( Table 2 ), a phase III study, evaluated pembrolizumab in combination with neoadjuvant ChT in early-stage, high-risk TNBC

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116 study, the examination of testicular tissue sections from rats treated with Vitamin E revealed the presence of typical seminiferous tubules, interspersed with a thin interstitial tissue containing Leydig cells and blood vessels

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In diseases characterized by chronic ER stress, such as diabetes and neurodegenerative disorders, modulating the UPR and autophagy could provide therapeutic benefits