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Curcumin induces brown fat-like phenotype in 3T3-L1 and primary white adipocytes

In the first reciprocal network, the KFGs were primarily enriched in pathways such as regulatory actin cytoskeleton, NF-kappa B signaling, Toll-like receptor signaling, and MAPK signaling (Figure 3C

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Guan R, Wang J, Li Z, Ding M, Li D, Xu G, Wang T, Chen Y, Yang Q, Long Z, Cai Z, Zhang C, Liang X, Dong L, Zhao L, Zhang H, Sun D, Lu W (2018) Sodium tanshinone IIA sulfonate decreases cigarette smoke-induced inflammation and oxidative stress via blocking the activation of MAPK/HIF-1alpha signaling pathway

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One study found that in high glucose conditions, E2 dose-dependently increased lactate and glucose-6-phosphate (G6P) production in human MCF-7 breast cancer cells, whereas in low glucose conditions, E2 dose-dependently reduced lactate production and enhanced TCA cycle flux (201)