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It is not approved for human consumption, medical treatment, diagnostic use, or veterinary application

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A Herxheimer reaction is generally temporary and may be followed by gradual improvement

Most involve a relatively small number of subjects, and few of the research teams seem to have actually published papers describing their methods and data

Those with pre-existing GI conditions, including gastroparesis, inflammatory bowel disease, or chronic pancreatitis, should avoid retatrutide entirely