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180 In an observational study that included 1,290 North American women, higher intake of omega-3 fatty acids from fish was correlated with shorter time to pregnancy, while higher intake of trans fatty acids was linked to lower pregnancy rates 181

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This and other immunosuppressive treatments may deviate the immune system from a Th1 to a Th2 type of response, reducing the number of regulatory T cells or altering the balance between T helper 17 (Th17) cells and regulatory T cells, and leading to overexpression of pro-inflammatory cytokines IL-17, IL-22, IL-23R, and IL-32 that are commonly seen in patients with AIDT (51-55)

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doi: 10.3390/ANTIOX11122444 88 BersukerKHendricksJMLiZMagtanongLFordBTangPHet al