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Description

Voltage-dependent anion channel (VDAC) opening mediates metabolite influx into mitochondria, increasing OXPHOS and ROS production, causing mitochondrial dysfunction (Wang et al., 2020)

Immunohistochemistry The endothelial cell marker CD31 was used to enable the evaluation of angiogenesis

J Clin Transl Hepatol 12(11):939948 Dutt S, Hamza I, Bartnikas TB

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The change in abundance of the barcoded clones can be traced by subsampling the cell population over time and quantifying the DNA barcodes by PCR and deep sequencing