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doi: 10.1371/journal.pgen.1004266 120 YanT.ChenM.ShenQ.LiL.FuX.PanQ.et al

Weight gain Weight gain itself wasnt reported as a side effect during clinical trials of Prolia

The importance of cancer cell metabolism and the limitations of conventional cancer therapies (e.g., resistance to chemotherapy or radiotherapy) have prompted the development of strategies aimed at targeting this biological process 2

However, we observed upregulated p63 expression in both basal and suprabasal layers of dysplasia and ESCC samples (Figure 1a)

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