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These contradicting reports concerning the potential positive and negative effects of GUS activities suggest that the gut bacterial GUSs all display a different spectrum of substrate preferences and that there are specific groups of GUSs for desirable and undesirable activities, with each displaying a unique spectrum of substrate preferences

Hussain G, Wang J, Rasul A et al (2020) Current status of therapeutic approaches against peripheral nerve injuries: a detailed story from injury to recovery

Huber, W., Messerschmitt, T

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In a recent study, we revealed that cysteine S-glutathionylation of the highly-conserved Cys188 residue of IL-1 positively regulates its bioactivity by preventing its irreversible ROS-elicited deactivation 11

Surprisingly, DHODH inhibitors Leflunomide and FK778 were initially reported to enhance the replication of HBV when tested in HepG2 and Huh7 cells, and this was confirmed in a recent report (179)