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Polyphenols as potent epigenetics agents for cancer

147 Overexpression of miR-144-3p could downregulate the GSH/GSSG ratio, increase the levels of ROS, Fe 2+ , and ACSL4, promote ferroptosis and thus reduce the metastasis of osteosarcoma cells, while high expression of ZIB1 plays the opposite role, 147 indicating that miR-144-3p and its downstream ZIB1 are involved in the development and metastasis of osteosarcoma mainly by interfering with iron metabolism and redox homeostasis

Mellen, H

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Use alone or as a makeup base

When cellular energy systems are functioning well, the body is better equipped to: Utilize stored energy more efficiently Support metabolic balance Maintain consistent energy levels Rather than forcing results, this approach focuses on improving how the system itself operates