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Gallstones are solid particles formed in the gallbladder, primarily composed of cholesterol, bilirubin, calcium carbonate, calcium phosphate, and trace elements [6, 7]

This mitochondrial dysfunction was accompanied by abnormal morphology of the brain mitochondria, and reduced synaptic density [382]

IFN- can also repress the expression of the NAD + -dependent deacetylase SIRT-1 (Li et al., 2012) which is a critical coordinator of cellular metabolism acting primarily by deacetylation

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Since only nine out of 108 amino acids were visible, we assume that the protein is unfolded in the precipitate, which is in agreement with the broad resonance lines mentioned above

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis