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and (c) a polynucleotide capable of hybridizing under stringent conditions to any one of the polynucleotides specified in (a)-(b), wherein said polynucleotide does not hybridize under stringent conditions to a nucleic acid molecule having a nucleotide sequence of only A residues or of only T residues

showed that curcumin effectively counteracts doxorubicin (DOX)-induced neurotoxicity by suppressing autophagy while reducing oxidative and endoplasmic reticulum stress, with these protective effects mediated through activation of the Keap1-Nrf2-ARE signaling pathway