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Coverage of blood vessels by astrocytic endfeet is reduced in major depressive disorder

71-women facial cream RCT and the 1998 Abdulghani et al

In these devices, contact of blood proteins with artificial surfaces such as the membrane of the oxygenator or tubing can cause blood clotting. Known as contact activation, this can lead to severe complications or even death and limits the use of artificial lungs for longer than a few days or weeks

But the most dramatic impact on aging is biological