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Addressing the inter-individual variation in response to consumption of plant food bioactives: towards a better understanding of their role in healthy aging and cardiometabolic risk reduction

Trends Biochem Sci (2019) 44:15366

Elko EA, Cunniff B, Seward DJ, et al

A Canadian study (published in JAMA) examined people with diabetic kidney disease who were given high doses of B12 and B6

Additionally, pyridoxine (B6), folate (B9), and cobalamin (B12) are indispensable coenzymes for the methylation of homocysteine to methionine, a process critical to nervous system function