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The intercellular adhesion molecule 1 (ICAM1) on BC cells can facilitate the formation of CTC clusters and mediate the trans-endothelial migration of tumor cells, thereby motivating lung colonization [186]

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Adenylyl cyclase (AC) is responsible for intracellular cAMP synthesis and MDL-12330A is a specific inhibitor of AC

Upon IR and NMR spectrometry analyses, in and extracts, two most important bioactive compounds, namely, saponin and hydroxy anthraquinone, have been reported [158]

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