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The review encompasses a broad range of topics, with key search terms including magnesium, Mg, Mg 2+ , sleep, sleep disorder, sleep disorders, sleep quality, sleep disturbances, sleep structure, sleep-wake, circadian rhythm, insomnia, idiopathic hypersomnia and narcolepsy, idiopathic hypersomnia or narcolepsy, obstructive sleep apnea, OSA, Restless legs syndrome/Willis-Ekbom disease, RLS/WED, therapeutic interventions, and sex differences

Research experiments and bioinformatic analyses suggest that serum or synovial fluid ferritin and GPX4 activity, among others (8, 99), might serve as combined diagnostic indicators, but large-scale cohort studies are essential to confirm their specificity and sensitivity (194)

Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-beta

BMC Syst Biol 7:103 Liu B, Teschemacher AG, Kasparov S (2017) Astroglia as a cellular target for neuroprotection and treatment of neuro-psychiatric disorders

This complex pathological syndrome may manifest as a sequela to diverse primary renal pathologies, including diabetic nephropathy (DN) and IgA nephropathy (IgAN), with its relentless progression orchestrated through cascading mechanisms of irreversible nephron depletion, progressive glomerular sclerosis, and extensive tubulointerstitial fibrosis, inevitably culminating in end-stage renal disease (ESRD) (Huang et al., 2025

Crichton, R