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Several radiomics-based ML models that combine MRI and clinical features can precisely predict pathological complete response to neoadjuvant chemotherapy, and thus inform timely modifications to therapy and individualized therapy design (251)

The GSH is recycled by glutathione reductase (GR) using NADPH from the pentose phosphate pathway

GPX4 can execute the oxidation/reduction steps by shifting its selenocysteine active site between an oxidized and a reduced state

S., Mishra, J

The Z polymorphism has shown an association with demyelinating and hypomyelinating conditions, potentially explaining the higher frequency of demyelinating diseases in individuals with A1AT pathological polymorphisms (65)