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[1] The authors framed the observed metabolic shifts as a direct effect on lipid handling in the model rather than appetite suppression

(2002, August)

cerevisiae strain BY4741 was transformed with full-length of P450 genes AG1IA_05136 , AG1IA_07929 , AG1IA_01023 , AG1IA_06336 , and AG1IA_07129 and GST gene AG1IA_07383

Zouboulis CC, Desai N, Emtestam L, Hunger RE, Ioannides D, Juhsz I, et al

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Compare that to oral rehydration, which can take several hours to make a dent if it works at all when your stomach is already upset