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The value for K (the elimination rate constant) calculated from the plasma concentration versus time curve is actually the value for Ka (the absorption rate constant)

ATP-based luminescence assays, such as the CellTiter-Glo 2.0 Assay, are the preferred platform for HTS drug screening because they offer the highest sensitivity (detecting 15100 cells/well), the simplest protocol (single reagent addition, 10-minute read time), and the lowest coefficient of variation across plate formats

That is useful for some applications but dangerous for others, particularly in people with cancer risk factors or metabolic disorders

doi:10.1074/jbc.R400001200

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