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Moreover, significant resistance to UV damage is appreciable at a molecular level, as indicated by the presence of a low UV-regulated transcriptome and an anti-tumoral molecular signature (Singh et al., 2021)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 131.Daussin F.N., Cuillerier A., Touron J., Bensaid S., Melo B., Rewashdy A.A., Vasam G., Menzies K.J., Harper M.E., Heyman E., et al

Assessment of tumor necrosis factor alpha blockade as an intervention to improve tolerability of dose-intensive chemotherapy in cancer patients

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Despite rapid advances, the current understanding of proteostasis remains fragmented, with most studies historically examining individual pathways or organ systems in isolation