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This work was supported by the Swedish Cancer Society (19 0370PJ, 22 31PJ01H to H.A

Alternatively, when cancer cells use GSH as a cysteine source, they rely less on these pathways (that is, xCT and TXNRD1)

Definitely returning for a follow up

Blemishes 2

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Upon activation, LXR induces cholesterol efflux and lipogenesis, but also exerts antiproliferative effects by downregulating cell cycle regulators such as S-phase kinase-associated protein 2 (Skp2), c-Myc, CDKs, and cyclins, and inducing hypophosphorylation of the tumor suppressor retinoblastoma protein (Rb), thereby halting epithelial cell proliferation [13, 14]