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A mechanistic model captures the emergence and implications of non-genetic heterogeneity and reversible drug resistance in ER+ breast cancer cells

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6.1.2 In vivo animal studies In animal studies, changes in the population of T lymphocytes mainly include an increase in the Th cell population during early pregnancy (149), a greater percentage of type 2 helper cells in relation to type 1 helper cells (148, 164), changes in the toll-like receptor (TLR) expression within thymic epithelial cells, and the synthesis of prostaglandins and proteins stimulated by interferon (150, 151)

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