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Examples are heart disease, prediabetes, or polycystic ovary syndrome ( PCOS )

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The role of xanthine in resistance development is still not understood and more studies are needed to understand its role and the pathways associated with it, as it may be a potential marker for treatment resistance in different cancers, especially breast cancer

Even with proper technique, sterile needles, and alcohol-swabbed stoppers, each puncture slightly increases contamination risk