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confounding conditions, e.g., tobacco smoking or carbon monoxide exposure, can also lower the P 50

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In short, it does not matter

I get pain there off and on as well as swelling

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Each dose draws 0.10 mL, so: 3.00 mL 0.10 mL = 30 doses per vial How long 30 doses lasts depends entirely on frequency which is the whole point of the phase schedule: Practically, roughly one vial per month covers the daily loading phase, and the same vial stretches much further once you drop to maintenance frequency