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Oxygen free radicals are also felt to have the ability to damage the sperm DNA and elevated levels of sperm DNA fragmentation (DFI) have been noted in men with oxidative stress

Stephan & Grun, Reference Stephan and Grun1989)

Summary Keywords Zingiber species, Alpinia species, gingerols, zerumbone, immunomodulatory, signaling pathways Citation Yuandani, Jantan I, Haque MA, Rohani AS, Nugraha SE, Salim E, Septama AW, Juwita NA, Khairunnisa NA, Nasution HR, Utami DS and Ibrahim S (2023) Immunomodulatory effects and mechanisms of the extracts and secondary compounds of Zingiber and Alpinia species: a review

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These mediators, together with activated cell surface receptors, amplify the inflammatory response and contribute to long-term lung tissue damage [68]

While freckles, sunspots, and age spots are common concerns, melasma stands out as particularly persistent and challenging to treat