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Some antioxidants may also influence insulin sensitivity , which is particularly relevant given the strong association between insulin resistance and NAFLD development

All analyses were done in duplicate and the samples were normalized to muscle protein concentration in each sample via a DC protein concentration assay (Bio-Rad, Hercules, CA)

In preclinical studies, CSPG biosynthesis inhibitors were shown to be efficient for rescuing OPC differentiation in vitro and accelerating remyelination in mice (Lau et al., 2012