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A study by Hamlin et al (2013) concluded that children living with ASD had low dietary intake of betaine and choline and this translated into significantly lower serum concentrations compared to age matched controls

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H.TangB

Lancet 2000;355:1787-8

Vanillin protects dopaminergic neurons against inflammation-mediated cell death by inhibiting ERK1/2, P38 and the NF-B signaling pathway

Labandeira-Garcia JL

Moreover, inhibition of the C5a-C5aR axis by using the C5 antibody diminished cerebral lesion and improved motor functions in a rat model of stroke [55], and treatment with C5a receptor antagonistPMX53 significantly decreases ischemia-induced apoptosis of primary mouse cortical neurons subjected to oxygenglucose deprivation (an in vitro model of hypoxiaischemia) [56]