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Jin et al., 2016

2025 Jun;642(8067):508-518

(2) Tissue histological analysis : After two weeks incubation with vehicle or MB, the EFT-412 issues were fixed in 10% formalin solution overnight and transferred in PBS solution on next day

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Visible results require patience - first subtle improvements appear at 4-6 weeks, noticeable anti-aging effects at 6-12 weeks, and maximum benefits at 12-24 weeks with diminishing returns thereafter