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Factors contributing to the suboptimal performance of drugs include the selection of drug targets, the use of biomarkers and animal models in experimental designs, and other issues such as late treatment initiation, dose-dependent side effects, challenges in BBB permeability, and the heterogeneous presentation of patients

Anandharamakrishnan, Computational Modelling and Nanoscale Processing Unit, National Institute of Food Technology, Entrepreneurship and Management Thanjavur Ministry of Food Processing Industries, Government of India, Thanjavur 613005, India

These types differ in their primary structure and in their biochemical properties but their tertiary structures own the same topology

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(PubMed) Nakanishi H, Kurosaki M, Tsuchiya K, et al

pyridoxine 7.98 mg Pyridoxine hydrochloride (Vitamin B6) 12.5 mg equiv