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However, excessive cytokine release can lead to a massive inflammatory cascade, which causes reversible or irreversible organ dysfunction and even death (73)

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Standard rTMS therapy for MDD typically involves daily sessions administered over a period of four to six weeks, with each session lasting approximately 30 to 40 min ( rTMS has also shown promise in treating bipolar disorder, particularly for depressive episodes

In other autoimmune diseases, natural antibodies are found against adrenergic, muscarinergic, and other G protein coupled receptors (GPCR) (30, 512)

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