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However, human safety data beyond 12 weeks does not yet exist long-term tolerability remains unknown

Hildebrandt W, Sauer R, Bonaterra G, Dugi KA, Edler L, Kinscherf R

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People With Pre-Existing Liver Disease Both dulaglutide (through its post-marketing hepatic enzyme signal) and high-dose IV glutathione (through hepatic conjugation load) warrant caution in people with Child-Pugh class A or B hepatic impairment

The structural analog SIH has only been studied in cell cultures, demonstrating protective effects against H 2 O 2 -induced damage in H9c2 cardiomyoblasts (Simunek et al., 2005)