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Overall, the finding that ICV JMV2959 can increase peripheral ghrelin at an identical dose that leads to decreased drinking [26] may support the notion that binge-like alcohol drinking occurs independently of peripheral ghrelin levels

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M+2 acetyl-CoA uptake assay in immunopurified ER ER were purified as described above from SLC33A1 knockout HEK293T expressing EMC3-mScarlet-3xHA (ER-tag) complemented with a vector control or SLC33A1 cDNA