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You're confirming the treatment plan is working, not making significant changes

Many of these nutritional migraine triggers have vasoactive properties (causes constriction or dilation of blood vessels)(Gallagher 2012), which is why they may contribute to migraine attacks

Vitamin B12 also has a low potential for toxicity, even at large doses, as the body doesnt store it, so its generally considered to be safe

Some studies, but not all, have reported an increased risk of MACE in association with use of testosterone replacement therapy in men

Semaglutide is contraindicated in patients with a personal or family history of certain types of thyroid cancer, specifically thyroid C-cell tumors such as medullary thyroid carcinoma (MTC), or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)

That is not a weakness in the research it is an accurate reflection of how complex the condition is