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The Journal of Sports Medicine and Physical Fitness, 55(4), 313319

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L-carnitine emerged as one of the few dietary supplements showing significant efficacy in reducing fatigue in ME/CFS patients according to a systematic review, notwithstanding methodological limitations such as small sample size and potential selection bias [136]

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The two major homocysteine-utilizing enzymes, methionine synthase and cystathionine -synthase, show reciprocal sensitivity to oxidative conditions (Mosharov et al., 2000)