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Li and Karin, 1999

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doi: 10.3390/antiox9080681, 93 HatamlehA

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While anti-CTLA-4 agents are believed to be more toxic than anti-PD-1/PD-L1 drugs, a definitive comparison is lacking due to their different therapeutic uses

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[5] [6] [7] This gene is a member of the glutathione peroxidase family encoding a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract

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For example, GshB has two protein clusters associated with it (PRK12458 and PRK05246), so if the first hit from RPS-Blast for a protein was any one of these clusters, the protein was assumed to be GshB

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In this same structure, there is the presence of clear cells, which are responsible for secretion and absorption of glycoproteins as well as the degradation of toxic substances

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