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found that during exercise, patients with long COVID showed decreased rates of fatty acid oxidation [32], consistent with other reports [48] that describe a general metabolic profile of impaired mitochondrial fatty acid and lipid catabolism in general, as well as a decrease in several amino acids that can fuel mitochondrial TCA cycle activity

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PMID: 23250957

As well as when patients with -thal were exogenously supplemented with vitamin E, researchers found that antioxidants could mitigate oxidative stress in erythrocytes through multiple targets, thereby impacting iron overload ( On the other hand, iron overload may also be an intermediate link in the interaction between ferroptosis and, IE in -thal

Below is a table to compare the side effect profiles: Personal experience goes a long way in how individuals deal with these side effects