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Description

Reiss, E

It is a synthetic version of the naturally occurring hormone Melanotan II, which is responsible for the production of melanin in the body

studies in cultured mouse kidney cells

HK was supported by the Takeda Science Foundation

(due to 1st pass effect) Not effective orally Hepatic metabolism, half life 1.5-2 hrs (this can result in CNS toxicity) Patients with CHF or hepatic disease will have higher plasma levels Major drug Interactions: MAOIs or ergot alkaloids (when using epinephrine containing solutions)